Urine pH and cystitis

After a lot of discussions about the need to control the urine pH and the impact of pH in case of cystitis, here you will find some information that medical and scientific research has validated on this subject.

PH is a unit of measurement that quantifies the acidity of a solution.

The scale of pH values goes from 0 to 14.

Neutrality corresponds to a value of 7.

The lowest values are called “acid”, the highest “basic” or “alkaline”.

NB:  food/drink/medicine pH does not necessarily correspond to their effect on the urinary pH (for example, lemon is an acidic food that alkalizes urine). To know the impact of a food on the urinary pH, it is necessary to consult PRAL indices that provide information about this “potential acidification”.

The physiological balance of urinary pH is between 4.5 and 7.5

In other words, urine is generally acid, but can reach a certain alkalinity according to the diet and the subject (age, state of health, physiological state, etc.). It is possible to measure urinary pH simply by using urine test strips (on sale).

NB: too basic urine (with a pH higher than 7.5) may be responsible for the formation of kidney stones. Such a pH value cannot be reached with diet alone so do not be scared. On the other hand, the regular consumption of acidifying foods in a tendential way can reduce urinary pH.

Now let’s see what role urinary pH plays in case of cystitis.

Cystitis is an INFLAMMATION of the bladder WITH OR WITHOUT bacterial infection.

Especially in case of recurrent cystitis, the inflammation may persist after the resolution of the infectious episode (giving the impression of a relapse).

NB: hence the fundamental importance of performing an urine culture test EVERY TIME we have the simptomatology to make sure the antibiotics intake is not unnecessary.

When a tissue is inflamed, it is essential to try to calm this inflammation. This can be done in two ways: with substances that will positively influence the reconstruction of the epithelium (for example, Cistiquer) and, of course, by avoiding another attack on the mucosa.

In case cystitis is due to a bacterial INFECTION:

– the responsible bacteria (E. Coli, Klebsiella, Pseudomonas, etc.) are acidophilic or, at least, acid germs. This means that they like acidic environments and they know how to resist in such situation and survive. So it is easy to understand why acidification is not a defense against bacterial attack.


In case of cystitis, urine acidification (with cranberry , uva ursi, etc.) is NOT a solution because:

– it will cause further damage on the mucosa with an eventual pain increase

– it will not destroy bacteria

It has been shown that when cystitis is managed with D-Mannose, this active ingredient acts on the uropathogenic germs potentiated in little acidic urine too.

For this reason, the formulation of Ausilium 20 PLUS is born from this study result and associates D-Mannose with an alkalizing urinary agent for a strengthening action against bacteria and a calming effect on the painful symptomatology.

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